MRTX1719 hydrochloride

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 3796

CAS [N.A.]

MF C23H18ClFN6O2.HCl
MW 501.34

Description

MRTX1719 is a potent and selective inhibitor of the PRMT5.MTA complex.

Cell Signaling & Oncology Epigenetics Endocrinology EC 2.1.1.125 PRMT

Inhibitor of the PRMT5.MTA complex

(R)-2-(4-(4-(aminomethyl)-1-oxo-1,2-dihydrophthalazin-6-yl)-1-methyl-1H-pyrazol-5-yl)-4-chloro-6-cyclopropoxy-3-fluorobenzonitrile hydrochloride

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[2630904-45-7]

Axon ID	Name	Description
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2831	EPZ 015666	Potent, selective and orally available inhibitor of PRMT5	€125.00
3692	PF-06939999 dihydrochloride	SAM competitive PRMT5 inhibitor	Inquire
3750	GSK3326595	Orally active, potent, selective, SAM uncompetitive, peptide competitive, slow binding inhibitor of protein arginine methyltransferase 5 (PRMT5)	Inquire
3754	JNJ-64619178 dihydrochloride	SAM-pocket binding (SAM Competitive) PRMT5 inhibitor	Inquire
3798	PF-06855800	SAM-pocket-binding (SAM competitive) PRMT5 inhibitor	Inquire
3919	GSK3368715 hydrochloride	A first-in-class, orally active, potent and selective, SAM-Noncompetive inhibitor of Type I Protein Arginine Methyltransferases (PRMTs)	Inquire