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Axon 3789
CAS [1373764-75-0]
MF C19H18N2O2MW 306.36
YH-306 blocks the activation of FAK and FAK-related signaling pathways, leading to the suppression of CRC growth and metastasis. In vitro, YH-306 significantly inhibited CRC cell migration, invasion, proliferation and colonization, and induced CRC cell apoptosis. In vivo, YH-306 depressed CRC growth and suppressed hepatic/pulmonary metastasis.
KEYWORDS: YH-306 | Supplier | FAK inhibitor | YH306 | YH 306 | CAS [1373764-75-0] | Non Selective (Phosphorylation substrates) | FAK | Inhibitor | Enzymes | TGFβ | Lung cancer | Breast cancer | Colorectal cancer | CRC | PI3K | Rac1
1-(3,4-Dihydro-1H-pyrido[3,4-b]indol-2(9H)-yl)-2-(4-hydroxyphenyl)ethanone
[1373764-75-0]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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