DS-3032 - Milademetan | DS-3032B

Based on 6 reference(s) in Google Scholar 8 10 6

Axon 3765

CAS [1398568-47-2]

MF C30H34Cl2FN5O4
MW 618.53

  • Purity: 99%
  • Optical purity: 99%
  • Soluble in DMSO
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DS-3032

Description

DS-3032 (Milademetan) is an orally available, potent and selective inhibitor of the p53-MDM2 (murine double minute 2) interaction.

* Sold in collaboration with Chemietek.

KEYWORDS: DS-3032 | Supplier | MDM2 inhibitor | Milademetan | DS-3032B | DS3032 | DS 3032 | DS3032B | DS3032B | CT-DS3032 | CAS [1398568-47-2] | p53 | HDM-MDM | Inhibitor | Enzymes | acute myeloid leukemia (AML) | acute lymphocytic leukemia (ALL) | chronic myeloid leukemia (CML) in blast phase | lymphoma | myelodysplastic syndrome (MDS)

Orally available, potent and selective inhibitor of the p53-MDM2 interaction

Chemical name

(3'R,4'S,5'R)-N-((3R,6S)-6-Carbamoyltetrahydro-2H-pyran-3-yl)-6''-chloro-4'-(2-chloro-3-fluoro-4-pyridinyl)-4,4-dimethyl-2''-oxo-1'',2''-dihydrodispiro(cyclohexane-1,2'-pyrrolidine-3',3''-indole)-5'-carboxamide

Source information

Sold in collaboration with Chemietek

Parent CAS No.

[1398568-47-2]

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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