LYC-55716

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Axon 3740

CAS [2055536-64-4]

MF C27H23F6NO6S
MW 603.53

  • Purity: 99%
  • Optical purity: 99% e.e.
  • Soluble in DMSO
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LYC-55716

Description

LYC-55716 is a first-in-class, oral, selective RORgamma (γ) agonist, and a novel immuno-oncology agent. The retinoic acid-related orphan receptor gamma (γ) (RORγ) is a nuclear receptor transcription factor that acts as an immune cell master control switch. RORγ agonists modulate gene expression to reprogram immune cells for improved function, as well as decrease immunosuppressive mechanisms, resulting in decreased tumor growth and enhanced survival in in vivo preclinical models of cancer.

* Sold in collaboration with Chemietek.

KEYWORDS: LYC-55716 | Supplier | RORγ agonist | LYC55716 | LYC 55716 | CT-LYC557 | CAS [2055536-64-4] | Retinoic Acid | ROR | Agonist | Receptors

Potent RORγ agonist

Chemical name

(S)-3-(6-(3-(difluoromethoxy)-5-fluorophenyl)-4-(3-(trifluoromethyl)phenylsulfonyl)-3,4-dihydro-2H-benzo[b][1,4]oxazin-2-yl)-2,2-dimethylpropanoic acid

Source information

Sold in collaboration with Chemietek

Parent CAS No.

[2055536-64-4]

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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