HBX 41,108 - HBX41108

Based on 8 reference(s) in Google Scholar 8 10 8

Axon 3732

CAS [924296-39-9]

MF C13H3ClN4O
MW 266.64

  • Purity: 99%
  • Soluble in DMSO and EtOH
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HBX 41,108

Description

HBX 41,108 is an inhibitor of USP7/HAUSP ubiquitin protease with an IC50 value of 424 nM. HBX 41,108 treatment stabilized p53, activated the transcription of a p53 target gene without inducing genotoxic stress, and inhibited cancer cell growth. Finally, HBX 41,108 induced p53-dependent apoptosis as shown in p53 wild-type and null isogenic cancer cell lines.

KEYWORDS: HBX 41,108 | Supplier | USP7 inhibitor | HBX41108 | HBX41,108 | HBX-41,108 | HBX 41108 | HBX-41108 | CAS [924296-39-9] | Non Selective (Ubiquitin peptides) | Deubiquitinase | Inhibitor | Enzymes | p53/Mdm2 | Ubiquitin-specific proteases

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Size Unit Price Stock
5 mg €110.00 In Stock
25 mg €390.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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