Based on 2 reference(s) in Google Scholar 8 10 2

Axon 3728

CAS [1258595-14-0]

MF C29H32F2N3O7P
MW 603.55

  • Purity: 99%
  • Soluble in DMSO



LHC-165 is an agonist (activator) of Toll-like Receptor 7 (TLR7), and an immuno-oncology modulator. TLR7 is a protein in the immune system that surveys and recognizes pathological malignance, and triggers the immune response by releasing infection-clearing cytokines if activated. It has demonstrated in mice that LHC-165 induced immune response, and reduced tumor growth, also showed signs of an abscopal effect.

KEYWORDS: LHC-165 | Supplier | Toll-like Receptor 7 agonist | LHC165 | LHC 165 | CT-LHC165 | CAS [1258595-14-0] | DNA-RNA | TLR7 | Agonist | Receptors

Agonist (activator) of Toll-like Receptor 7

Chemical name

3-(5-Amino-2-(4-(2-(3,3-difluoro-3-phosphonopropoxy)ethoxy)-2-methylphenethyl)benzo[f][1,7]naphthyridin-8-yl)propanoic acid

Source information

Sold in collaboration with Chemietek

Parent CAS No.


The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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