MIK665

Based on 9 reference(s) in Google Scholar 8 10 9

Axon 3713

CAS [1799631-75-6]

MF C47H44ClFN6O6S
MW 875.41

  • Purity: 99%
  • Optical purity: 99%
  • Soluble in DMSO
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MIK665

Description

MIK665 is a clinical-stage, BH3-Groove binding Mcl-1 inhibitor, potently and selectively binding to the protein target with Ki in picomolar range. Demonstrate in vitro and in vivo antitumor efficacy in Mcl-1 dependent cancer models. Achieve superior activity and enhanced solid tumor response when applied in combination with Bcl-2 inhibitors such as ABT-199 (Axon 2141) or BCL-201 (Axon 3714).

* Sold in collaboration with Chemietek.

KEYWORDS: MIK665 | Supplier | BH3-Groove binding Mcl-1 inhibitor | MIK-665 | MIK-665 | S-64315 | S 64315 | CT-MIK665 | CAS [1799631-75-6] | Non Selective | Mcl-1 | Inhibitor | Proteins

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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