DKM 2-93

Based on 4 reference(s) in Google Scholar 8 10 4

Axon 3709

CAS [65836-72-8]

MF C11H14ClNO3
MW 243.69

  • Purity: 98%
  • Soluble in DMSO and EtOH
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DKM 2-93

Description

DKM 2-93 is a relatively selective inhibitor of UBA5 with an IC50 value of 430 μM. Specifically, DKM 2-93 is a covalent ligand that impairs pancreatic cancer cell survival and in vivo tumor growth through covalently modifying the catalytic cysteine of the UBA5, thereby inhibiting its activity as a protein that activates the ubiquitin-like protein UFM1 to UFMylate proteins.

KEYWORDS: DKM 2-93 | Supplier | UBA5 inhibitor | DKM2-93 | DKM293 | CAS [65836-72-8] | Non Selective (Ubiquitin peptides) | Ubiquitin Ligase (E1) | Inhibitor | Enzymes | Pancreatic cancer | Ubiquitin-like modifier activating enzyme 5

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10 mg €70.00 In Stock
50 mg €120.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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