PF-06873600 - Ebvaciclib

Based on 4 reference(s) in Google Scholar 8 10 4

Axon 3693

CAS [2185857-97-8]

MF C20H27F2N5O4S
MW 471.52

  • Purity: 99%
  • Optical purity: 99% e.e.
  • Soluble in DMSO

PF-06873600

Description

PF-06873600 (Ebvaciclib) is an orally bioavailable, potent, and selective inhibitor of CDK2, CDK4 and CDK6, with Ki values at 0.1 nM, 1.2 nM and 0.1 nM, respectively.

* Sold in collaboration with Chemietek.

KEYWORDS: PF-06873600 | Supplier | CDK2/4/6 inhibitor | Ebvaciclib | PF06873600 | PF 06873600 | CT-PF0687 | CAS [2185857-97-8] | Cyclin Dependent (CDK) | CDK | Inhibitor | Enzymes

CDK inhibitor (4, 6, and 8 specific)

Chemical name

6-(Difluoromethyl)-8-((1R,2R)-2-hydroxy-2-methylcyclopentyl)-2-(1-(methylsulfonyl)piperidin-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one

Source information

Sold in collaboration with Chemietek

Parent CAS No.

[2185857-97-8]

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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