E-7766

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 3689

CAS [2242635-03-4]

MF C24H26F2N10O8P2S2.2NH3
MW 780.66

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in water
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E-7766

Description

E-7766 (E7766) is a structurally novel class of macrocyclic molecule, metabolically stable, specific, and potent (Kd in lower nM, on par with that of the natural ligand 2′,3′-cGAMP (Axonxx) agonist for both human and mouse STING (Stimulator of Interferon Genes). Exhibits broad pan‐genotypic activity in all major human STING variants. Demonstrates potent antitumor activity with long lasting immune memory response in a mouse liver metastatic tumor model.

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KEYWORDS: E-7766 | STING agonist | E7766 | E 7766 | CT-E7766 | CAS [2242635-03-4] | [2242635-02-3] | DNA-CDN | STING | Agonist | Proteins

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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