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RSL3 - 1S,3R-RSL3

Based on 60 reference(s) in Google Scholar 8 10 60

Axon 3611

CAS [1219810-16-8]

MF C23H21ClN2O5
MW 440.88

  • Purity: 99%
  • Optical purity: 99.6% d.e.
  • Soluble in DMSO and EtOH

RSL3

Description

RSL3 is a GPX4 inhibitor and ferroptosis inducer. RSL3 exhibited selective lethality against cells with HRASV12. A negative control (1R,3R)-RSL3 is available as Axon 3617.

KEYWORDS: RSL3 | Supplier | GPX4 inhibitor | 1S,3R-RSL3 | K601 | CAS [1219810-16-8] | RAS proteins | Ferroptosis | Inhibitor | Proteins | Oncogenic-RAS-synthetic-lethality | Glutathione peroxidase 4 | PhGPx | Ferroptotic cancer cell death

GPX4 inhibitor; Ferroptosis inducer

Chemical name

(1S,3R)-Methyl 2-(2-chloroacetyl)-1-(4-(methoxycarbonyl)phenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate

Parent CAS No.

[1219810-16-8]

Order
Size Unit Price Stock
5 mg €90.00 In Stock
25 mg €300.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €140.00 In Stock
2 x 25 mg €480.00 In Stock
Need more? Bulk Inquiry

Related Products

Axon ID Name Description From price
2293 Ferrostatin 1 Potent inhibitor of erastin-induced ferroptosis €85.00
2990 Liproxstatin-1 Potent inhibitor of ferroptosis €80.00
3427 SRS11-92 Inhibitor of ferroptosis €90.00
3617 1R,3R-RSL3 (negative control) Negative control of 1S,3R-RSL3 as GPX4 inhibitor €90.00
4018 FSEN1 Uncompetitive FSP1 inhibitor €120.00
3896 ML162 Covalent GPX4 inhibitor; Ferroptosis inducer €90.00

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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