Micheliolide - MCL

Based on 43 reference(s) in Google Scholar 8 10 43

Axon 3607

CAS [68370-47-8]

MF C15H20O3
MW 248.32

  • Purity: 100%
  • Optical purity: Optically pure
  • Soluble in DMSO



Micheliolide, a guaianolide sesquiterpene lactone, is an inhibitor of NF-κB pathway activation leading to downregulation of major inflammatory mediator expression such as TNFα and IL-1β. Moreover, MCL has been reported as inhibitor of acute leukemic cells. The prodrug of MCL, ACT001 is also available as Axon 3590.

KEYWORDS: Micheliolide | Supplier | NF-κB inhibitor | MCL | CAS [68370-47-8] | NF-κB | Inhibitor | Transcription Factors | Inflammatory bowel diseases | IBD | Inflammation | Colitis-associated cancer

Size Unit Price Stock
5 mg €120.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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