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MCUF-651

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 3600

CAS [2747162-85-0]

MF C17H22F2N4OS
MW 368.44

  • Purity: 99%
  • Soluble in 0.1N HCl(aq), DMSO and EtOH

MCUF-651

Description

MCUF-651 is a selective and orally bioavailable PAM of guanylyl cyclase A receptor (GC-A) with an EC50 value of 0.45 µM in HEK293 GC-A cells. MCUF-651 exhibits therapeutic activity in human hypertension and heart failure ex vivo.

Keywords: MCUF-651 | Supplier | GC-A PAM | MCUF651 | MCUF 651 | CAS [2747162-85-0] | Atrial natriuretic peptide (ANP) | Guanylate cyclase | PAM | Enzymes | Cardiovascular disease | Hypertension | Heart failure | GC-A/cGMP signaling pathway | NPR1 | GUCY2A

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5 mg €130.00 In Stock
25 mg €460.00 In Stock
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2 x 5 mg €230.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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