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Axon 3595
CAS [1428862-33-2]
MF C21H29N5O2.C2H2O4MW 473.52
Usmarapride is a potent, selective and orally bioavailable 5-HT4 receptor partial agonist with an EC50 value of 44 nM. Usmarapride showed high selectivity against ganglionic 5-HT3 receptor and other closely related receptors and good pharmacokinetics in rats, dogs, and healthy humans. It also showed promising in vivo efficacy in animal models of cognition. Additionally, Usmarapride increased neuroprotective sAPPα levels and may possess disease-modifying potential.
KEYWORDS: Usmarapride | Supplier | 5-HT4 receptor partial agonist | SUVND4010 | SUVN-D4010 | CAS [1428862-33-2] | [1428862-32-1] | [2415652-93-4] | [2415652-92-3] | Serotonin | 5-HT4 | Agonist | Receptors | Alzheimer's Disease
2-(1-Isopropyl-1H-indazol-3-yl)-5-(1-(3-methoxypropyl)piperidin-4-yl)-1,3,4-oxadiazole oxalate
[1428862-32-1]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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