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Axon 3594

CAS [2407860-35-7]

MF C22H13F6NO3
MW 453.33

  • Purity: 99%
  • Optical purity: 100% e.e.
  • Soluble in DMSO and EtOH



ErSO is an orally bioavailable activator of the anticipatory unfolded protein response (a-UPR). ErSO acts through ERα to elicit strong and sustained cytotoxic activation of the a-UPR. Moreover, ErSO hyperactivates the ERα-dependent a-UPR in ERα+ cancer cells leading to eradication of ERα+ breast tumors in multiple mouse models. The inactive (S)-enantiomer (Axon 3704)  is available as negative control.

KEYWORDS: ErSO | Supplier | a-UPR activator | CAS [2407860-35-7] | Unfolded Protein Response (Non Selective) | Estrogen (ER) | Ligand | Receptors | Metastatic estrogen receptor α (ERα)-positive breast cancer | Breast tumor | Src kinase | UPR

Size Unit Price Stock
5 mg €180.00 In Stock
25 mg €720.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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