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Axon 3591

CAS [2561494-77-5]

MF C24H21N5O4
MW 443.45

  • Purity: 98%
  • Soluble in DMSO



UNC6934 is a potent and selective chemical probe targeting the N-terminal PWWP (PWWP1) domain of NSD2 (Kd value of 91 nM). Moreover, UNC6934 disrupted the interaction between NSD2-PWWP1 and nucleosomal H3K36me2 in a dose-dependent manner with an IC50 value of 104 nM. The negative control UNC7145 is also available as Axon 3592.

KEYWORDS: UNC6934 | Supplier | NSD2-PWWP1 antagonist | UNC 6934 | UNC-6934 | CAS [2561494-77-5] | Histone | HMTase | Inhibitor | Enzymes | Multiple myeloma | WHSC1 | MMSET | PHD

Potent and selective chemical probe targeting NSD2-PWWP1

Chemical name


Parent CAS No.


Size Unit Price Stock
5 mg €120.00 In Stock
25 mg €420.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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