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Axon 3587

CAS [2499663-01-1]

MF C25H28N6O2
MW 444.53

  • Purity: 99%
  • Soluble in 0.1N HCl(aq), DMSO and EtOH



STM2457 is a first-in-class, highly potent and selective catalytic inhibitor of the m6A writer METTL3 (IC50 of 16.9 nM for METTL3/METTL14 catalytic activity).

KEYWORDS: STM2457 | Supplier | METTL3 inhibitor | STM 2457 | STM-2457 | CAS [2499663-01-1] | DNA-RNA | RNA methyltransferase | Inhibitor | Enzymes | Myeloid leukaemia | AML | N6-adenosine-methyltransferase | METTL3-METTL14 methyltransferase complex | m6A writer

First-in-class, highly potent and selective catalytic METTL3 inhibitor

Chemical name


Parent CAS No.


Size Unit Price Stock
5 mg €130.00 In Stock
25 mg €490.00 In Stock
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Size Unit Price Stock
2 x 5 mg €220.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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