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Axon 3575
CAS [2296729-00-3]
MF C30H30F2N6O3MW 560.59
AMG510 is a highly potent, selective, orally bioavailable, well-tolerated and covalent KRASG12C inhibitor with an IC50 value of 68 nM (p-ERK).
KEYWORDS: AMG510 | Supplier | KRAS-G12C inhibitor | Sotorasib | AMG 510 | AMG-510 | CAS [2296729-00-3] | [2252403-56-6] | GTP | KRAS | Inhibitor | Enzymes | Lumakras | RAS
4-((S)-4-Acryloyl-2-methylpiperazin-1-yl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidin-2(1H)-one
[2296729-00-3]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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