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Axon 3573
CAS [36791-04-5]
MF C8H12N4O5MW 244.20
Ribavirin is a guanosine analog that interferes with the replication of RNA and DNA viruses. Moreover, ribavirin binds directly to eIF4E with micromolar affinity in vitro, competes efficiently with eIF4E:m7G mRNA cap binding in vitro and in cells, and specifically disrupts eIF4E:m7G functions in the transport and translation of eIF4E-regulated genes at low micromolar concentrations in cells, with consequent down-regulation of oncogenic proteins, cell-cycle arrest, and suppression of eIF4E-mediated transformation in vitro and in vivo.
KEYWORDS: Ribavirin | Supplier | Antiviral agent | 1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide | CAS [36791-04-5] | DNA-RNA | Inhibitor | Hepatitis C | COVID-19 | Coronavirus
1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1H-1,2,4-triazole-3-carboxamide
[36791-04-5]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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