Ribavirin - 1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide

Based on 16463 reference(s) in Google Scholar 8 10 16463

Axon 3573

CAS [36791-04-5]

MF C8H12N4O5
MW 244.20

  • Purity: 100%
  • Optical purity: Optically pure
  • Soluble in water and DMSO
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Ribavirin

Description

Ribavirin is a guanosine analog that interferes with the replication of RNA and DNA viruses. Moreover, ribavirin binds directly to eIF4E with micromolar affinity in vitro, competes efficiently with eIF4E:m7G mRNA cap binding in vitro and in cells, and specifically disrupts eIF4E:m7G functions in the transport and translation of eIF4E-regulated genes at low micromolar concentrations in cells, with consequent down-regulation of oncogenic proteins, cell-cycle arrest, and suppression of eIF4E-mediated transformation in vitro and in vivo.

KEYWORDS: Ribavirin | Supplier | Antiviral agent | 1-β-D-Ribofuranosyl-1,2,4-triazole-3-carboxamide | CAS [36791-04-5] | DNA-RNA | Inhibitor | Hepatitis C | COVID-19 | Coronavirus

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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