THZ1 dihydrochloride

Based on 78 reference(s) in Google Scholar 8 10 78

Axon 3561

CAS [2422107-17-1]

MF C31H28ClN7O2.2HCl
MW 566.05

  • Purity: 98%
  • Soluble in DMSO

THZ1 dihydrochloride


THZ1 dihydrochloride is a first covalent inhibitor of CDK7 (IC50 value of 3.2 nM) which employs a unique mechanism, combining ATP-site and allosteric covalent binding, as means of attaining potency and selectivity for CDK7. The free base is also available as THZ1 (Axon 3560).

KEYWORDS: THZ1 dihydrochloride | Supplier | CDK7 inhibitor | THZ-1 dihydrochloride | THZ 1 dihydrochloride | CAS [1604810-83-4] | [2422107-17-1] | Cyclin Dependent (CDK) | CDK | Inhibitor | Enzymes | T-cell acute lymphoblastic leukaemia | T-ALL | RUNX1

Size Unit Price Stock
5 mg €110.00 In Stock
25 mg €330.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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