KCa modulator RA-2

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 3516

CAS [1867107-62-7]

MF C22H16F2O6
MW 414.36

  • Purity: 98%
  • Soluble in 0.1N NaOH(aq), DMSO and EtOH
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KCa modulator RA-2

Description

RA-2 is a potent and selective KCa2/3 pan inhibitor with negative-gating modulator properties (IC50 values of 17 and 2 nM for KCa3.1 and KCa2.3, respectively). RA-2 inhibited EDH-type dilations in porcine coronary arteries (PCAs) and was found not to increase blood pressure in telemetry recordings despite reducing heart rate (HR).

KEYWORDS: KCa modulator RA-2 | KCa2/3 inhibitor | KCa modulator RA2 | KCa modulator RA 2 | CAS [1867107-62-7] | Potassium | KCa3.1 | KCa2 | Opener | Ion Channels | Hypotension | Hyperemia | Chronic inflammation

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50 mg €420.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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