Mycophenolate mofetil - RS61443 | TM-MMF

Based on 8587 reference(s) in Google Scholar 8 10 8587

Axon 3498

CAS [128794-94-5]

MF C23H31NO7
MW 433.49

  • Purity: 99%
  • Soluble in 0.1N NaOH(aq), 0.1N HCl(aq), DMSO and EtOH
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Mycophenolate mofetil

Description

Mycophenolate mofetil is an immunosuppressive prodrug which is hydrolyzed by esterases in the intestine and blood to release mycophenolic acid (MPA). MPA is a potent, selective, noncompetitive inhibitor of the type 2 isoform of inosine monophosphate dehydroxygenase (IMPDH) expressed in activated human T and B lymphocytes.

KEYWORDS: Mycophenolate mofetil | Supplier | IMPDH inhibitor | RS61443 | TM-MMF | RS 61443 | RS-61443 | CAS [128794-94-5] | [116680-01-4] | Inosine monophosphate (IMP) | IMPDH | Inhibitor | Enzymes | Rejection of organ allografts | Organ transplant

Oral prodrug of MPA; Potent, selective, noncompetitive IMPDH inhibitor

Chemical name

(E)-2-Morpholinoethyl 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoate

Parent CAS No.

[128794-94-5]

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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