PRL-3 inhibitor - BR1

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3436

CAS [893449-38-2]

MF C17H11Br2NO2S2
MW 485.21

Purity: 98%
Soluble in DMSO

PRL-3 inhibitor

Description

PRL-3 inhibitor is a selective inhibitor of PRL-3 with an IC50 value of 0.9 μM. PRL-3 inhibitor strongly inhibited the migration and invasion of PRL-3 overexpressing colon cancer cells without exhibiting cytotoxicity.

KEYWORDS: PRL-3 inhibitor | supplier | PRL-3 inhibitor | BR1 | BR 1 | BR-1 | CAS [893449-38-2] | Non Selective (Tyrosine Specific Phosphomonoesters) | PRL | Inhibitor | Enzymes | Colorectal cancer metastasis

JH Ahn et al. Synthesis and biological evaluation of rhodanine derivatives as PRL-3 inhibitors. Bioorg Med Chem Lett. 2006 Jun 1;16(11):2996-9.

G Min et al. Rhodanine-based PRL-3 inhibitors blocked the migration and invasion of metastatic cancer cells. Bioorg Med Chem Lett. 2013 Jul 1;23(13):3769-74.

Cell Signaling & Oncology EC 3.1.3.48

Selective inhibitor of PRL-3

Chemical name

5-(5-Bromo-2-(2-bromobenzyloxy)benzylidene)-2-thioxothiazolidin-4-one

Parent CAS No.

[893449-38-2]

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PRL-3 inhibitor - BR1

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