Based on 1 reference(s) in Google Scholar 8 10 1

Axon 3263

CAS [1386162-69-1]

MF C22H25N3O3
MW 379.45

  • Purity: 99%
  • Soluble in DMSO



ML417 is a potent, highly selective D3 dopamine receptor agonist with an EC50 value of 38 nM. ML417 promotes potent D3R-mediated β-arrestin translocation, G protein-mediated signaling, and pERK phosphorylation with minimal effects on other GPCR-mediated signaling. Also, ML417was found to exhibit neuroprotection against toxin-induced neurodegeneration of dopaminergic neurons.

KEYWORDS: ML417 | Supplier | D3 agonist | ML 417 | ML-417 | CAS [1386162-69-1] | Dopamine | D3 | Agonist | Receptors | Neuropsychiatric disorder

Size Unit Price Stock
10 mg €110.00 In Stock
50 mg €390.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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