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Axon 3259
CAS [2421117-98-6]
MF C28H26N4O4S2MW 546.66
BC-DXI-843 is a potent AIMP2-DX2 inhibitor (IC50 value of 0.92 μM) with more than 100-fold selectivity over AIMP2 in a luciferase assay. Moreover, BC-DXI-843 demonstrated in vivo efficacy in a tumor xenograft mouse model (H460 cells).
KEYWORDS: BC-DXI-843 | Supplier | AIMP2-DX2 inhibitor | BC-DXI843 | BC-DXI 843 | CAS [2421117-98-6] | Protein synthesis | Inhibitor | Proteins | Lung cancer | HSP70 | AIMP2 splicing variant | Ubiquitination | Aminoacyl-tRNA synthetase
(S)-3-(1H-Indol-3-yl)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-2-(4-methylphenylsulfonamido)propanamide
[2421117-98-6]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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