Finasteride - MK-906

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3240

CAS [98319-26-7]

MF C23H36N2O2
MW 372.54

Purity: 99%
Optical purity: Optically pure
Soluble in DMSO

Finasteride

Description

Finasteride is a potent, reversible inhibitor of the rat type 1 5α-reductase with a Ki value of 10.2 nM. Finasteride has been shown to reduce the size of human benign prostatic hyperplasia (BPH) by inhibiting the intraprostatic conversion of testosterone to 5 alpha-dihydrotestosterone.

JR Carlin et al. High-performance liquid chromatographic determination of N-(2-methyl-2-propyl)-3-oxo-4-aza-5 alpha-androst-1-ene-17 beta-carboxamide, a 4-azasteroid, in human plasma from a phase I study. J Chromatogr. 1988 May 13;427(1):79-91.

B Azzolina et al. Inhibition of rat alpha-reductases by finasteride: evidence for isozyme differences in the mechanism of inhibition. J Steroid Biochem Mol Biol. 1997 Apr;61(1-2):55-64.

H Weisser et al. 5 alpha-reductase inhibition by finasteride (Proscar) in epithelium and stroma of human benign prostatic hyperplasia. Steroids. 1994 Nov;59(11):616-20.

Potent, reversible inhibitor of 5α-reductase

Chemical name

(4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-tert-Butyl-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide

Parent CAS No.

[98319-26-7]

Order

Size	Unit Price	Stock
50 mg	€50.00	In Stock

Special Offers

Size	Unit Price	Stock
2 x 50 mg	€60.00	In Stock

Need more? Bulk Inquiry

Related Products

Axon ID	Name	Description
1204	EBPC	Aldose reductase inhibitor	€82.00
1822	N6022	Inhibitor of S-nitrosoglutathione reductase (GSNOR)	€90.00
2043	Atorvastatin calcium	Inhibitor of HMG-CoA reductase	€60.00
2544	S3QEL 2	Suppressor of superoxide production from mitochondrial complex III	€60.00
2883	APPA	Aldose reductase inhibitor	€105.00

Customer Support

Customer Services

About Axon Medchem

Contact Us

Finasteride - MK-906

Description

Chemical name

Parent CAS No.

Customer Support

About Axon Medchem

Download Product Catalog

Follow Us

Customer Support

Customer Services

About Axon Medchem

Contact Us

Finasteride - MK-906

Description

Chemical name

Parent CAS No.

Related Products

Customer Support

About Axon Medchem

Download Product Catalog

Follow Us

Send us a message

Contact Us