Pemetrexed disodium - LY231514 disodium

Based on 2486 reference(s) in Google Scholar 8 10 2486

Axon 3162

CAS [137281-23-3]

MF C20H19N5Na2O6
MW 471.37

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in water
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Pemetrexed disodium

Description

Pemetrexed disodium is a antifolate antimetabolite which potently inhibits dihydrofolate reductase (DHFR), thymidylate synthase (TS), and glycinamide ribonucleotide formyltransferase (GARFT) with Ki values of 7.0 nM, 109 nM and 9,300 nM, respectively. Pemetrexed disodium is active as an inhibitor of tumor growth in vitro and in vivo.

KEYWORDS: Pemetrexed disodium | supplier | DHFR/TS/GARFT inhibitor | LY231514 disodium | LY 231514 disodium | LY-231514 disodium | CAS [137281-23-3] | [150399-23-8] | Deoxyuridine monophosphate (dUMP) | TYMS | Inhibitor | Enzymes | Alimta

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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