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Axon 3095
CAS [1187990-87-9]
MF C24H21N5O4MW 443.45
MK-8617 is a potent, orally active pan-inhibitor of HIF-PHD with IC50 values of 1 nM, 1 nM, and 14 nM for PHD1, PHD2 and PHD3, respectively. MK-8617 advanced to human clinical studies as an oral treatment for anemia.
KEYWORDS: MK-8617 | supplier | PHD inhibitor | MK8617 | MK 8617 | CAS [1187990-87-9] | Hypoxia-signaling cascade | PHD (HIF) | Inhibitor | Enzymes | Anemia
N-(Bis(4-methoxyphenyl)methyl)-4-hydroxy-2-(pyridazin-3-yl)pyrimidine-5-carboxamide
[1187990-87-9]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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