NSC 95397

Based on 69 reference(s) in Google Scholar 8 10 69

Axon 3086

CAS [93718-83-3]

MF C14H14O4S2
MW 310.39

  • Purity: 98%
  • Soluble in DMSO
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NSC 95397

Description

NSC 95397 is a potent and selective Cdc25 dual specificity phosphatase (DUSP) inhibitor with in vitro Ki values of 32, 96, and 40 nM for Cdc25A, -B, and -C, respectively. NSC 95397 was 125- to 180-fold more selective for Cdc25A than VH1-related dual-specificity phosphatase or protein tyrosine phosphatase 1b, respectively. Moreover, NSC 95397 showed significant growth inhibition against human and murine carcinoma cells and blocked G(2)/M phase transition.

KEYWORDS: NSC 95397 | supplier | Cdc25 inhibitor | NSC95397 | NSC-95397 | CAS [93718-83-3] | Non Selective (Serine-Threonine and Tyrosine Specific Phosphodiesters) | DUSP | Inhibitor | Enzymes | Cell cycle progression | Cdk | Carcinoma

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5 mg €70.00 In Stock
25 mg €220.00 In Stock
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2 x 5 mg €120.00 In Stock
2 x 25 mg €360.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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