CPI-444 - Ciforadenant | V 81444

Based on 4 reference(s) in Google Scholar 8 10 4

Axon 3085

CAS [1202402-40-1]

MF C20H21N7O3
MW 407.43

  • Purity: 99%
  • Optical purity: 100% e.e.
  • Soluble in DMSO
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CPI-444

Description

CPI-444 is potent, selective and oral A2A adenosine receptor (A2aR) antagonist inhibitor (Ki value of 3.5 nM) which has demonstrated high selectivity and ability to block A2aR in in vitro studies. CPI-444 dramatically enhances immunologic responses in models of checkpoint therapy and ACT in cancer. Moreover, CPI-444 induces antitumor responses and augments efficacy to anti-PD-(L)1 and anti-CTLA-4 in preclinical models.

KEYWORDS: CPI-444 | supplier | A2A antagonist | Ciforadenant | V 81444 | CPI444 | CPI 444 | V81444 | V-81444 | CAS [1202402-40-1] | Adenosine | A2A | Antagonist | Receptors

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Size Unit Price Stock
5 mg €85.00 In Stock
25 mg €285.00 In Stock
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Size Unit Price Stock
2 x 5 mg €140.00 In Stock
2 x 25 mg €420.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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