NPB

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Axon 3079

CAS [2247491-97-8]

MF C29H31Cl2N3O2
MW 524.48

  • Purity: 99%
  • Soluble in DMSO
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NPB

Description

NPB is a potent, site-specific inhibitor of Bcl-2-associated death promoter (BAD) phosphorylation with efficacy in tumor models. NPB reduced phosphorylation of BAD-Ser99 and enhanced caspase 3/7 activity with associated loss of cell viability in various human cancer cell lines derived from mammary, endometrial, ovarian, hepatocellular, colon, prostatic, and pancreatic carcinoma.

KEYWORDS: NPB | supplier | BAD inhibitor | CAS [2247491-97-8] | Non Selective | Bcl | Inhibitor | Proteins

Potent, site-specific Bcl-2-associated death promoter (BAD) inhibitor

Chemical name

N-Cyclopentyl-3-((4-(2,3-dichlorophenyl)piperazin-1-yl)(2-hydroxyphenyl)methyl)benzamide

Parent CAS No.

[2247491-97-8]

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Size Unit Price Stock
10 mg €130.00 In Stock
50 mg €390.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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