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Axon 3079
CAS [2247491-97-8]
MF C29H31Cl2N3O2MW 524.48
NPB is a potent, site-specific inhibitor of Bcl-2-associated death promoter (BAD) phosphorylation with efficacy in tumor models. NPB reduced phosphorylation of BAD-Ser99 and enhanced caspase 3/7 activity with associated loss of cell viability in various human cancer cell lines derived from mammary, endometrial, ovarian, hepatocellular, colon, prostatic, and pancreatic carcinoma.
KEYWORDS: NPB | supplier | BAD inhibitor | CAS [2247491-97-8] | Non Selective | Bcl | Inhibitor | Proteins
N-Cyclopentyl-3-((4-(2,3-dichlorophenyl)piperazin-1-yl)(2-hydroxyphenyl)methyl)benzamide
[2247491-97-8]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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