B591 - PI3K inhibitor B591

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 3055

CAS [1498412-41-1]

MF C25H24Br2N2O
MW 528.28

  • Purity: 99%
  • Soluble in DMSO



B591 is a specific pan-PI3K inhibitor with potent inhibitory activity against class I PI3K isoforms (IC50 values of 1.300, 0.364, 0.107 and 1.580 μM for PI3Kα, PI3Kβ, PI3Kβγ, PI3Kδ, respectively), which showed effective inhibition of cellular PI3K/mTOR signaling pathway and robust antitumor activity in a set of cancer cell lines. Cancer stem cells (CSCs) targeting agent.

KEYWORDS: B591 | supplier | PI3K inhibitor | PI3K inhibitor B591 | B 591 | B-591 | PI3K inhibitor B 591 | PI3K inhibitor B-591 | CAS [1498412-41-1] | [1499285-30-1] | Phosphatidylinositol | PI3K | Inhibitor | Enzymes | CSC | Cancer stem cell

Potent, specific class I PI3K inhibitor

Chemical name

3-(2-Bromobenzyl)-1-((2,3-dihydrobenzofuran-5-yl)methyl)-5,6-dimethyl-1H-benzo[d]imidazol-3-ium bromide

Parent CAS No.


Size Unit Price Stock
10 mg €125.00 In Stock
50 mg €395.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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