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Axon 3053

CAS [2244904-70-7]

MF C25H28N4O2S
MW 448.58

  • Purity: 98%
  • Optical purity: 100% e.e.
  • Soluble in DMSO



BAY-293 is a potent, selective and cell-active inhibitor of KRAS-SOS1 interaction with an IC50 value of 21 nM. BAY-293 efficiently inhibited pERK levels in K-562 cells after incubation for 60 min without affecting total protein levels of ERK. A synergistic effect is observed between BAY-293 and ARS-853 in a KRASG12C-mutated cancer cell line.

KEYWORDS: BAY-293 | supplier | KRAS-SOS1 inhibitor | BAY293 | BAY 293 | CAS [2244904-70-7] | GTP | KRAS | Inhibitor | Enzymes | Son of sevenless | SOS1

Potent, selective and cell-active inhibitor of KRAS-SOS1 interaction

Chemical name


Parent CAS No.


Size Unit Price Stock
5 mg €140.00 In Stock
25 mg €490.00 In Stock
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Size Unit Price Stock
2 x 5 mg €220.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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