ARN 3236

Based on 2 reference(s) in Google Scholar 8 10 2

Axon 3041

CAS [1613710-01-2]

MF C19H16N2O2S
MW 336.41

  • Purity: 98%
  • Soluble in DMSO
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ARN 3236

Description

ARN 3236 is a potent, selective, ATP-competitive, and orally available inhibitor of SIK2 (IC50 value of < 1 nM) and inhibits SIK1 and SIK3 with IC50 values of 21.63 and 6.63 nM, respectively. Moreover, ARN 3236 inhibits ovarian cancer cell growth and sensitizes ovarian cancer cells and xenografts to paclitaxel by inhibiting centrosome splitting and AKT/survivin signaling.

KEYWORDS: ARN 3236 | supplier | SIK2 inhibitor | ARN3236 | ARN-3236 | CAS [1613710-01-2] | Non Selective (Phosphorylation Substrates) | SIK | Inhibitor | Enzymes | Ovarian cancer

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Size Unit Price Stock
5 mg €95.00 In Stock
25 mg €335.00 In Stock
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2 x 5 mg €150.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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