Abivertinib - AC 0010 | Avitinib

Based on 13 reference(s) in Google Scholar 8 10 13

Axon 3040

CAS [1557267-42-1]

MF C26H26FN7O2
MW 487.53

  • Purity: 99%
  • Soluble in DMSO

Abivertinib

Description

Abivertinib is a potent, selective, orally available and irreversible third-generation EGFR inhibitor with an IC50 value of 0.18 nM against EGFR L858R/T790M double mutations.

KEYWORDS: Abivertinib | supplier | EGFR inhibitor | AC 0010 | Avitinib | AC0010 | AC-0010 | CAS [1557267-42-1] | EGF | EGFR | Inhibitor | Receptors | NSCLC | T790M

Potent oral, irreversible, third-generation EGFR TKI with selectivity for mutant EGFRs

Chemical name

N-(3-(2-(3-Fluoro-4-(4-methylpiperazin-1-yl)phenylamino)-7H-pyrrolo[2,3-d]pyrimidin-4-yloxy)phenyl)acrylamide

Parent CAS No.

[1557267-42-1]

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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