LUF7244

Based on 3 reference(s) in Google Scholar 8 10 3

Axon 3032

CAS [1821638-43-0]

MF C20H15ClN2O3
MW 366.80

  • Purity: 98%
  • Soluble in DMSO

LUF7244

Description

LUF7244 is a potent negative allosteric modulator of Kv 11.1 (hERG) channels with an IC50 value of 3.9 μM. Moreover, LUF7244 was found to be a negative allosteric modulator of dofetilide (Axon 2103) binding to the Kv11.1 channel with the strongest effect at 10 μmol/L.

KEYWORDS: LUF7244 | supplier | Kv11.1 channel NAM | LUF 7244 | LUF-7244 | CAS [1821638-43-0] | Potassium | Kv11.1 | NAM | Ion Channels | Ventricular arrhythmia | Afterdepolarization | Torsades de pointes arrhythmia

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Size Unit Price Stock
10 mg €140.00 In Stock
50 mg €490.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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