NIC3 - NAC1 inhibitor NIC3

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3031

CAS [494830-67-0]

MF C26H36N2O4
MW 440.58

  • Purity: 99%
  • Soluble in DMSO



NIC3 is an inhibitor of nucleus accumbens–associated protein-1 (NAC1) homodimerization. Specifically, NIC3 has the ability to selectively bind with the conserved Leu90 of NAC1 and to inhibit NAC1 dimerization, resulting in proteasomal degradation of the NAC1 protein. NIC3 shows potent effects on sensitizing drug-resistant tumor cells to chemotherapy and reinforcing the antimetastatic efficacy of the antiangiogenic agent bevacizumab.

KEYWORDS: NIC3 | supplier | NAC1 inhibitor | NAC1 inhibitor NIC3 | NIC 3 | NIC-3 | CAS [494830-67-0] | DNA | NAC1 | Inhibitor | Transcription Factors | BTBD14B

Size Unit Price Stock
10 mg €90.00 In Stock
50 mg €290.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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