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AC1903

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3026

CAS [831234-13-0]

MF C19H17N3O
MW 303.36

Purity: 99%
Soluble in DMSO and EtOH

AC1903

Description

AC1903 is a selective inhibitor of TRPC5 with an IC50 value of 14.7 μM.

KEYWORDS: AC1903 | Supplier | TRPC5 blocker | AC 1903 | AC-1903 | CAS [831234-13-0] | Calcium | TRPC5 | Blocker | Ion Channels | Progressive kidney disease | Chronic kidney disease

Y Zhou et al. A small-molecule inhibitor of TRPC5 ion channels suppresses progressive kidney disease in animal models. Science. 2017 Dec 8;358(6368):1332-1336.

SH Sharma et al. Design, synthesis and characterization of novel N-heterocyclic-1-benzyl-1H-benzo[d]imidazole-2-amines as selective TRPC5 inhibitors leading to the identification of the selective compound, AC1903. Bioorg Med Chem Lett. 2019 Jan 15;29(2):155-159.

Diabetes & Metabolism Unclassified TRPC

Selective TRPC5 inhibitor

Chemical name

1-Benzyl-N-(furan-2-ylmethyl)-1H-benzo[d]imidazol-2-amine

Parent CAS No.

[831234-13-0]

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Size	Unit Price	Stock
10 mg	€95.00	In Stock
50 mg	€285.00	In Stock

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Axon ID	Name	Description	From price
2458	Clemizole	Inhibitor of the transient receptor potential channel TRPC5		€75.00
3633	Ononetin	Potent and selective TRPM3 antagonist		€60.00

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