Based on 18 reference(s) in Google Scholar 8 10 18

Axon 3025

CAS [1199236-64-0]

MF C19H27ClFN3O2
MW 383.89

  • Purity: 98%
  • Soluble in 0.1N HCl (aq) and DMSO



Z944 is a highly selective, orally available T-type Ca2+ channel blocker with IC50 values of 50 to 160 nM for hCa V 3.1, hCa V 3.2, and hCa V 3.3 T types. Upon administration to GAERS animals, Z944 potently suppressed absence seizures by 85 to 90% via a mechanism distinct from the effects of ethosuximide and valproate.

KEYWORDS: Z944 | supplier | Ca channel blocker | Z 944 | Z-944 | CAS [1199236-64-0] | Calcium | Non Selective | Blocker | Ion Channels | Absence seizure

Highly selective, orally available Ca2+ channel blocker (T-type voltage gated)

Chemical name


Parent CAS No.


Size Unit Price Stock
10 mg €130.00 In Stock
50 mg €470.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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