JavaScript seems to be disabled in your browser.
You must have JavaScript enabled in your browser to utilize the functionality of this website.

Axon Medchem

All

Home
Products
- Shop By Category
- Featured Products
- Shop By Alphabet
  - A
  - B
  - C
  - D
  - E
  - F
  - G
  - H
  - I
  - J
  - K
  - L
  - M
  - N
  - O
  - P
  - Q
  - R
  - S
  - T
  - U
  - V
  - W
  - X
  - Y
  - Z
  - #
Support
- - Customer Support
  - Customer Services
Contact
- About Axon Medchem
- Contact Us

DS44960156

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 3020

CAS [2361327-08-2]

MF C20H15NO5
MW 349.34

Purity: 99%
Soluble in 0.1N NaOH(aq) and DMSO

DS44960156

Description

DS44960156 is a MTHFD2 inhibitor with an IC50 value of 1.6 μM and >18 fold selectivity over MTHFD1.

KEYWORDS: DS44960156 | supplier | MTHFD2 inhibitor | DS 44960156 | DS-44960156 | CAS [2361327-08-2] | NADP+ | NADP+ | Inhibitor | Enzymes | Methylenetetrahydrofolate dehydrogenase 2

J Kawai et al. Structure-Based Design and Synthesis of an Isozyme-Selective MTHFD2 Inhibitor with a Tricyclic Coumarin Scaffold. ACS Med Chem Lett. 2019 May 24;10(6):893-898.

Cell Signaling & Oncology NADP+ EC 1.5.1.5

Selective MTHFD2 inhibitor

Chemical name

4-(5-Oxo-2,3,4,5-tetrahydro-1H-chromeno[3,4-c]pyridine-3-carbonyl)benzoic acid

Parent CAS No.

[2361327-08-2]

Order

Size	Unit Price	Stock
5 mg	€180.00	In Stock

Need more? Bulk Inquiry

Please wait...