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Axon 3006
CAS [1218942-37-0]
MF C21H19ClN4O2MW 394.85
GKT137831 is a first-in-class dual Nox1/4 inhibitor with Ki values of 110 nM and 140 nM for human Nox1 and Nox4, respectively. Moreover, GKT137831 is a potent inhibitor of fibrosis and hepatocyte apoptosis.
KEYWORDS: GKT137831 | supplier | Nox1/4 inhibitor | Setanaxib | GKT831 | GKT 137831 | GKT-137831 | GKT 831 | GKT-831 | CAS [1218942-37-0] | NADPH | NADPH | Inhibitor | Enzymes | Diabetic nephropathy
2-(2-Chlorophenyl)-4-(3-(dimethylamino)phenyl)-5-methyl-1H-pyrazolo[4,3-c]pyridine-3,6(2H,5H)-dione
[1218942-37-0]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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