Based on 2 reference(s) in Google Scholar 8 10 2

Axon 3000

CAS [1446817-84-0]

MF C20H22F9N3O2
MW 507.39

  • Purity: 98%
  • Soluble in DMSO



ABX-1431 is a highly potent, selective, and orally available, CNS-penetrant MGLL (MAGL) inhibitor with an IC50 value of 0.014 µM. In vivo, ABX-1431 inhibits MGLL activity in rodent brain (ED50 value of 0.5-1.4 mg/kg), increases brain 2-AG concentrations, and suppresses pain behavior in the rat formalin pain model.

KEYWORDS: ABX-1431 | Supplier | MAGL inhibitor | ABX1431 | ABX 1431 | CAS [1446817-84-0] | 2-arachidonoyl glycerol (2-AG) | MAGL | Inhibitor | Enzymes | MGLL

Highly potent, selective, brain-penetrant, and orally available MAGL inhibitor

Chemical name

1,1,1,3,3,3-Hexafluoropropan-2-yl 4-(2-(pyrrolidin-1-yl)-4-(trifluoromethyl)benzyl)piperazine-1-carboxylate

Parent CAS No.


Size Unit Price Stock
5 mg €135.00 In Stock
25 mg €450.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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