TH 34

Based on 3 reference(s) in Google Scholar 8 10 3

Axon 2996

CAS [2196203-96-8]

MF C15H16N2O2
MW 256.30

  • Purity: 98%
  • Soluble in DMSO
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TH 34

Description

TH 34 is a selective inhibitor of HDAC6, HDAC8, and HDAC10 with IC50 values of 4.6 µM, 1.9 µM, and 7.7 µM, respectively. TH 34 effectively and selectively eliminates high-grade neuroblastoma cells while sparing non-transformed human cells. In neuroblastoma cell lines as well as primary neuroblastoma cells, it markedly induces DNA damage, followed by differentiation and G2/M phase cell cycle arrest at later timepoints, eventually leading to cell death.

KEYWORDS: TH 34 | supplier | HDAC6/8/10 inhibitor | TH34 | TH-34 | CAS [2196203-96-8] | Histone | HDAC | Inhibitor | Enzymes | Neuroblastoma

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Size Unit Price Stock
10 mg €120.00 In Stock
50 mg €420.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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