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USP7-USP47 inhibitor - USP7/47 inhibitor compound 14

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 2991

CAS [1247825-37-1]

MF C18H11Cl2N3O3S3
MW 484.40

  • Purity: 98%
  • Soluble in DMSO

USP7-USP47 inhibitor

Description

USP7-USP47 inhibitor is a selective dual inhibitor of the cancer-related deubiquitylating proteases USP7 and USP47 with IC50 values of 0.42 µM and 1.0 µM for USP7 and USP47, respectively. USP7-USP47 inhibitor exhibited enhanced potency against HCT-116 cells and modestly accelerated the degradation of polβ protein in HeLa cells.

KEYWORDS: USP7-USP47 inhibitor | supplier | USP7 inhibitor | USP7/47 inhibitor compound 14 | CAS [1247825-37-1] | Non Selective (Ubiquitin peptides) | Deubiquitinase | Inhibitor | Enzymes | HCT-116 | HeLa | Polβ

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Size Unit Price Stock
5 mg €90.00 In Stock
25 mg €290.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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