Apatinib - Apatinib mesylate | YN968D1 | Rivoceranib mesylate

Based on 70 reference(s) in Google Scholar 8 10 70

Axon 2849

CAS [1218779-75-9]

MF C25H27N5O4S
MW 493.58

  • Purity: 99%
  • Soluble in DMSO

Apatinib

Description

Potent and selective inhibitor of VEGFR2 tyrosine kinase (IC50 value of 1 nM). Apatinib could also potently suppress the activities of RET, c-KIT and c-Src with IC50 values of 0.13, 0.429 and 0.53 μM, respectively. In vivo, apatinib alone and in combination with chemotherapeutic agents effectively inhibited the growth of several established human tumor xenograft models with little toxicity.

KEYWORDS: Apatinib | supplier | VEGFR2 inhibitor | Apatinib mesylate | YN968D1 | Rivoceranib mesylate | CAS [1218779-75-9] | [811803-05-1] | VEGF | VEGFR | Inhibitor | Receptors | Angiogenesis

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10 mg €125.00 In Stock
50 mg €375.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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