Based on 25 reference(s) in Google Scholar 8 10 25

Axon 2828

CAS [33985-68-1]

MF C24H20N2O
MW 352.43

  • Purity: 99%
  • Soluble in DMSO



C-DIM5 is a Nur77 agonist. Activation of the orphan nuclear receptor Nur77 by C-DIM5 is associated with decreased cancer cell survival, induction of apoptosis, induced expression of the apoptosis gene/protein TRAIL, and inhibited tumor growth in vivo. C-DIM5 induces G0-G1–phase to S-phase arrest in Panc1 cells, and this is accompanied by Nur77-dependent induction of the cyclin-dependent kinase inhibitor p21.

KEYWORDS: C-DIM5 | supplier | Nur77 agonist | DIM-C-pPhOCH3 | CDIM5 | CAS [33985-68-1] | Intracellular Transcription Factors | Nurr | Agonist | Receptors | TRAIL

Size Unit Price Stock
10 mg €95.00 In Stock
50 mg €325.00 In Stock
Need more? Bulk Inquiry

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Please wait...