JavaScript seems to be disabled in your browser.
You must have JavaScript enabled in your browser to utilize the functionality of this website.

Axon Medchem

All

Home
Products
- Shop By Category
- Featured Products
- Shop By Alphabet
  - A
  - B
  - C
  - D
  - E
  - F
  - G
  - H
  - I
  - J
  - K
  - L
  - M
  - N
  - O
  - P
  - Q
  - R
  - S
  - T
  - U
  - V
  - W
  - X
  - Y
  - Z
  - #
Support
- - Customer Support
  - Customer Services
Contact
- About Axon Medchem
- Contact Us

BAY-678

Based on 2 reference(s) in Google Scholar 8 10 2

Axon 2822

CAS [675103-36-3]

MF C20H15F3N4O2
MW 400.35

Purity: 99%
Optical purity: 99% ee
Soluble in DMSO

BAY-678

Description

BAY-678 is a potent, selective and orally active human neutrophil elastase (HNE) inhibitor (IC50 value of 20 nM).

KEYWORDS: BAY-678 | supplier | HNE inhibitor | BAY678 | BAY 678 | CAS [675103-36-3] | Non Selective (Serine Peptide Bonds) | HNE | Inhibitor | Enzymes

F von Nussbaum et al. Freezing the Bioactive Conformation to Boost Potency: The Identification of BAY 85-8501, a Selective and Potent Inhibitor of Human Neutrophil Elastase for Pulmonary Diseases. ChemMedChem. 2015 Jul;10(7):1163-73.

Immunology Miscellaneous Pain & Inflammation EC 3.4.21.37 HNE

Potent, selective and orally active human neutrophil elastase (HNE) inhibitor

Chemical name

(R)-5-(5-Acetyl-6-methyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydropyrimidin-4-yl)picolinonitrile

Parent CAS No.

[675103-36-3]

Order

Size	Unit Price	Stock
10 mg	€105.00	In Stock
50 mg	€390.00	In Stock

Need more? Bulk Inquiry

Related Products

Axon ID	Name	Description	From price
1269	SSR 69071	HLE inhibitor		€145.00
2364	GW 311616A	Potent, selective and orally active human neutrophil elastase (HNE) inhibitor		€120.00

Please wait...