Ensemble Compound 159

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 2800

CAS [1449208-36-9]

MF C42H51ClN6O6
MW 771.34

  • Purity: 97%
  • Optical purity: Optically pure
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Ensemble Compound 159

Description

Ensemble Compound 159 is a peptide inhibitor of IL-17A. Ensemble Compound 159 binds to IL-17A and/or inhibits formation of the IL-17A–IL-17RA complex through an ELISA assay, an HT29-GROα cell based functional assay, a rheumatoid arthritis synovial fibroblast (RASF) assay, and surface plasmon resonance (SPR, Kd < 100 nM) based biophysical binding assessment. Moreover, Ensemble Compound 159 was reported to have efficacy in vivo.

KEYWORDS: Ensemble Compound 159 | supplier | IL-17A inhibitor | Cp159 | Cp-159 | Cp 159 | CAS [1449208-36-9] | Interleukin | IL-17 | Inhibitor

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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