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Axon 2800
CAS [1449208-36-9]
MF C42H51ClN6O6MW 771.34
Ensemble Compound 159 is a peptide inhibitor of IL-17A. Ensemble Compound 159 binds to IL-17A and/or inhibits formation of the IL-17A–IL-17RA complex through an ELISA assay, an HT29-GROα cell based functional assay, a rheumatoid arthritis synovial fibroblast (RASF) assay, and surface plasmon resonance (SPR, Kd < 100 nM) based biophysical binding assessment. Moreover, Ensemble Compound 159 was reported to have efficacy in vivo.
KEYWORDS: Ensemble Compound 159 | supplier | IL-17A inhibitor | Cp159 | Cp-159 | Cp 159 | CAS [1449208-36-9] | Interleukin | IL-17 | Inhibitor
(2S)-3-(2-chlorophenyl)-2-(2-phenylacetamido)-N-(4-(((9R)-7,10,13,21-tetraoxo-8,11,14,20-tetraazaspiro[4.17]docosan-9-yl)methyl)phenyl)propanamide
[1449208-36-9]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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