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Axon 2766
CAS [1802148-05-5]
MF C23H24N4O4MW 420.46
AZD7986 is a highly potent, reversible, and selective DPP1 inhibitor (pIC50 value of 8.4). Moreover, good species crossover was seen with the DPP1 enzyme (pIC50 values of 7.6, 7.7, 7.8 and 7.8 for mouse, rat, dog and rabbit, respectively). Clinical candidate for COPD.
Keywords: AZD7986 | Supplier | DPP1 inhibitor | Brensocatib | AZD-7986 | AZD 7986 | INS1007 | INS-1007 | INS 1007 | PZ1130 | PZ-1130 | PZ 1130 | CAS [1802148-05-5] | Axon Medchem | Axon 2766 | Non Selective (Proline peptide bonds) | DPP1 | Inhibitor | Enzymes | Cathepsin C | CatC | COPD | DPPI
(S)-N-((S)-1-Cyano-2-(4-(3-methyl-2-oxo-2,3-dihydrobenzo[d]oxazol-5-yl)phenyl)ethyl)-1,4-oxazepane-2-carboxamide
[1802148-05-5]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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