Based on 594 reference(s) in Google Scholar 8 10 594

Axon 2754

CAS [293754-55-9]

MW 481.33

  • Purity: 98%
  • Soluble in DMSO



T0901317 is selective liver X receptor (LXR) agonist (EC50 value of 20 nM). Oral administration of T0901317 to mice and hamsters showed that LXR activated the coordinate expression of major fatty acid biosynthetic genes (lipogenesis) and increased plasma triglyceride and phospholipid levels in both species. Complementary studies in cell culture and animals suggested that the increase in plasma lipids occurs via LXR-mediated induction of the sterol regulatory element-binding protein 1 (SREBP-1) lipogenic program.

KEYWORDS: T0901317 | supplier | LXR agonist | T 0901317 | T-0901317 | CAS [293754-55-9] | Metabolism | LXR | Agonist | Receptors | Liver X Receptor | Lipogenesis

Liver X receptor (LXR) agonist

Chemical name


Parent CAS No.


Size Unit Price Stock
10 mg €75.00 In Stock
50 mg €205.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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